Captain Jean-Luc Picard and crew engage in their most thrilling adventure yet. They call themselves the Borg — a half-organic, half-machine collective with a sole purpose: to conquer and assimilate all races. Led by their seductive and sadistic queen, the Borg are headed to Earth with a devious plan to alter history. Picard's last encounter with the Borg almost killed him. Now, he wants vengeance. But how far will he go to get it?

Patrick Stewart (Captain Jean-Luc Picard)
Jonathan Frakes (Commander William T. Riker)
Brent Spiner (Lieutenant Commander Data)
LeVar Burton (Lieutenant Commander Geordi La Forge)
Michael Dorn (Lieutenant Commander Worf)
Marina Sirtis (Commander Deanna Troi)
Gates McFadden (Commander Beverly Crusher, M.D.)
Alfre Woodard (Lily Sloane)
James Cromwell (Zefram Cochrane)
Alice Krige (The Borg Queen)

Michael Horton (Lieutenant Daniels)
Neal McDonough (Lieutenant Hawk)
Marnie McPhail (Lieutenant Eiger)
Dwight Schultz (Lieutenant Reginald Barclay)
Robert Picardo (Emergency Medical Holographic Program)
Adam Scott (Defiant Conn Officer)
Jack Shearer (Admiral Hayes)
Eric Steinberg (Lieutenant Paul Porter)
Patti Yasutake (Lieutenant Alyssa Ogawa)

• First Contact between Vulcans and Humans occurred on April 5, 2063.
  
• The new Sovereign-class U.S.S. Enterprise NCC-1701-E debuts.
  
• The crew has a new Starfleet uniform, black with grey shoulders and a V-neck; a colored turtleneck indicates their division.
  
• La Forge's VISOR has been replaced with occular implants.
  
• Robert Picardo (EMH on Star Trek: Voyager) has a cameo as the Enterprise-E EMH, which Crusher activates to create a diversion. Ethan Phillips, Voyager's Neelix, has a cameo as the Maitre D' in the Dixon Hill holodeck sequence.
  
• Though he had directed several television episodes before this, this is the motion picture directorial debut of Jonathan Frakes.