En route to Azati Prime, Archer and his crew encounter another roadblock: a trans-dimensional disturbance. The fate of Enterprise is in Dr. Phlox's hands as the rest of the crew must be induced into a coma in order to survive the four day trip.

Porthos

• Phlox narrates the events of the episode in a letter to his friend Dr. Lucas.
  
• Affected by the disturbance, Phlox hallucinates T'Pol is running the ship with him, while Xindi-Insectoids are trying to get them.
  
• Fake T'Pol can talk to Phlox, but she does not interact with anything nor does she provide him with guidance running the ship (e.g., she does not touch her food, can't find the plasma injectors, and is confused about various ship controls.)
  
• Phlox does not realize she is a hallucination until he walks her to her quarters after waking Archer and Trip, and discovers the real T'Pol asleep in bed.
  
• Running the ship alone, Phlox attends to the crew, walks around naked, and watches The Court Jester on movie night.
  
• Phlox gets to say "I'm a physician, not an engineer!" while panicking over the warp engines.
  
• This episode's storyline is very similar to the Voyager episode "One" featuring Seven of Nine.