An alien relay station enables Voyager to contact the U.S.S. Prometheus, an experimental Federation starship in the Alpha Quadrant, but when the Doctor is transmitted aboard, he finds the crew has been killed and the ship taken over by Romulans.

Andy Dick (EMH Mark-II)
Judson Scott (Commander Rekar)
Valerie Wildman (Sub-Commander Nevala)
Tiny Ron (Idrin)
Tony Sears (Starfleet Officer)

• This episode is the beginning of a long story arc featuring the Hirogen, who appear in the next 5 episodes.
  
• The ancient communications array stretches across the Delta Quadrant into the Beta Quadrant, almost to the Alpha Quadrant.
  
• The Prometheus-class Federation starship U.S.S. Prometheus is a new prototype deep space tactical vessel.
  
• The CGI model rendered by Foundation Imaging had an incorrect registry of NX-59650. According to Mike Okuda, it should have been NX-74913, which is used on the bridge screens.
  
• The Doctor tells EMH-2 that he has had sexual relations...He made an "addition to his program."
  
• The EMH-2 states "I'm a doctor, not a commando!"
  
• The Doctor spoke directly with Starfleet Command to tell them about Voyager and he was sent back with the message that "Voyager is no longer alone." (*sniff*)
  
• Judson Scott played Joachim in Star Trek II: The Wrath of Khan (He was not given credit for the role because he demanded billing with the main stars or none at all. He got none at all.) He also appeared in the Next Generation episode "Symbiosis".